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  Melanie Sekeres
  Assistant Professor, Department of Psychology & Neuroscience, Baylor University
   
  PhD. Physiology University of Toronto (2012)
  MSc. Physiology University of Toronto (2008)
   
  B.Sc. Psychology Trent University (2002)
   
  Email & Address:
 

melanie_sekeres@balyor.edu

   
 

The Baylor University
One Bear Place, 97334
Waco, Texas, 76798

Telephone: (254) 710-2234

 

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EDUCATION
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2008 – 2012
PhD, Dept. of Physiology, University of Toronto, Toronto, ON, Canada
Supervisor: Dr. Sheena A. Josselyn
Thesis Title: CREB-mediated enhancement of hippocampus-dependent memory consolidation and reconsolidation

2006 – 2008
MSc (transfer), Dept. of Physiology, University of Toronto, Toronto, ON, Canada
Supervisor: Dr. Sheena A. Josselyn
Thesis Title: Dorsal hippocampal CREB is both necessary and sufficient for spatial memory

1998 – 2002     
BSc, Dept. of Psychology, Trent University, Peterborough, ON, Canada


PEER REVIEWED PUBLICATIONS
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Winocur, G., Sekeres, M., Binns, M. Moscovitch, M. (2012) Hippocampal lesions produce both non-graded and temporally-graded retrograde amnesia in the same rats.  (in press, Hippocampus, HIPO-12-223).

Sekeres, M., Sargin, D., Mercaldo, V., Frankland, P.W., Josselyn, S.A. (2012). Increasing CRTC1 function in the dentate gyrus during memory formation or reactivation increases memory strength without compromising memory quality. (in press, Journal of Neuroscience, JN-RM-1419-12R1).

Cole CJ, Mercaldo V, Restivo L, Yiu AP, Sekeres MJ, Han JH, Vetere G, Pekar T, Ross PJ, Neve RL, Frankland PW, Josselyn SA. (2012).  MEF2 negatively regulates learning-induced structural plasticity and memory formation. Nature Neuroscience 15:1255 - 64.

Sekeres, M., Sargin, D., Ross, P.J., Josselyn, S.A. (2012). The role of CREB and CREB co-activators in memory formation. In K.P. Giese (Ed.), The Memory Mechanisms in Health and Disease: Mechanistic Basis of Memory. World Scientific Publishing.

Rochon, P., Sekeres, M., Hoey, J., Lexchin, J., Ferris, LE., Moher, D., Wu, W., Kalkar, S., Van Laethem, M., Gruneir, A., Gold, J., Maskalyk, J., Streiner, D.L., Tabak, N., Chan, AW. (2011). Investigator experiences with financial conflicts of interest in clinical trials. Trials, 12:9.

Sekeres, M.J., Neve, R., Frankland, P.W., Josselyn, S.A. (2010). Dorsal hippocampal CREB is both necessary and sufficient for spatial memory. Learning & Memory, 17(6): 280-3.

Winocur, G.,  Moscovitch, M., Rosenbaum, R. S.,  Sekeres, M (2010). Investigation of the effects of hippocampal lesions in rats on pre- and post-operatively acquired spatial memory in a complex environment. Hippocampus, 20 (12): 1350-65.

Rochon, P., Sekeres, M., Lexchin, J., Moher, D , Wu, W., Kalkar, S., Van Laethem, M., Hoey, J., Chan, AW.,  Gruneir, A., Gold, J., Maskalyk, J., Streiner, D.L., Tabak, N., Ferris, LE. (2010). Institutional financial conflicts of interest at Canadian academic health science centres: A national survey.
Open Medicine, 4(3): 134-8.

Rochon, P., Hoey, J., Chan, AW., Ferris, LE., Lexchin, J., , Kalkar, S., Sekeres, M., Wu, W., Van Laethem, M., Gruneir, A., Maskalyk, J., Streiner, D.L., Gold, J.,  Moher, D (2010). Financial Conflicts of Interest Checklist 2010 for clinical research studies. Open Medicine, 4(1): 69-9.

Winocur, G, Moscovitch, M., Rosenbaum, R.S., Sekeres, M. (2010). A study of remote spatial memory in aged  rats. Neurobiology of Aging (1):143-50.

Winocur, G, Frankland, P.W., Sekeres, M., Fogel, S.,  Moscovitch, M. (2009). Manipulating context-specificity in a memory reconsolidation paradigm: Selective effects of hippocampal lesions. Learning & Memory 16(11):722-9.

Sekeres, M., Gold, J., Chan, AW, Lexchin, J., Moher, D., Maskalyk, J., Ferris, L., Taback, N., Van Laethem, M., Rochon, P. (2008). Poor reporting of scientific leadership information in clinical trial registers. PLoS One, 3:2, e.1610. 

Lexchin, J., Sekeres, M., Van Laethem, M., Ferris, L., Chan, AW, Moher, D., Gold, J., Maskalyk, J., Taback, N., Rochon, P. (2008). National evaluation of policies on individual financial conflicts of interest in Canadian academic health science centres. Journal of General Internal Medicine, 23(11):1896-903.

Winocur, G, Moscovitch, M., Sekeres, M. (2007). Memory consolidation or transformation: Context manipulation and hippocampal representations of memory. Nature Neuroscience, 10, 555-557.

Winocur, G., Wojtowicz, J.M., Sekeres, M., Snyder, J.S., Wang, S. (2006). Inhibition of neurogenesis interferes with hippocampus-dependent memory function. Hippocampus, 16: 296–304.

Winocur, G, Moscovitch, M., Fogel, S., Rosenbaum, R.S., Sekeres, M. (2005). Preserved spatial memory after hippocampal lesions: effects of extensive experience in a complex environment. Nature Neuroscience, 8, 273 – 275.

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NON-PEER REVIEWED PUBLICATIONS
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Sekeres MJ, Neve RL, Josselyn SA (2009). Increasing CREB in the dorsal hippocampus is sufficient to induce spatial memory. Frontiers in Neuroscience. Conference Abstract: B.R.A.I.N. platform in Physiology poster day 2009. doi:0.3389/conf.neuro.03.2009.17.051
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FUNDING & AWARDS
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2012-2013            
Early Researcher Award, $2750
Ontario Research Coalition

2012                      
Jack Kraicer Doctoral Award, $1000
Physiology Department, University of Toronto

2011 - 2012         
Doctoral Completion Award, $18,000
University of Toronto

2011-2012           
Dr. Joe A. Connolly Memorial Award, $6000
Faculty of Medicine, University of Toronto

2011-2012           
Hayden Hantho Award, $5000
Faculty of Medicine, University of Toronto

2011-2012           
Margaret & Howard Gamble Research Grant, $5000 (declined)
Faculty of Medicine, University of Toronto

2011-2012           
SCACE Graduate Fellowship in Alzheimer’s Research, $5000 (declined)
Faculty of Medicine, University of Toronto

2011                      
University of Toronto Neuroscience Program Travel Award, (Society for Neuroscience)  
University of Toronto $500

2011                      
Restracomp Travel Award, $1,000
The Hospital for Sick Children

2011                      
School of Graduate Studies Conference Grant, $150
University of Toronto
               
                                         
2008 - 2011         
CIHR Frederick Banting and Charles Best Canada Graduate Scholarships, $35,000/year
Doctoral Award, CIHR

2010                      
Restracomp Travel Award, $1,000
The Hospital for Sick Children

2010                      
Exceptional Trainee Award, Program in Neurosciences & Mental Health, $500
The Hospital for Sick
Children

2010                      
University of Toronto Neuroscience Program Travel Award (Canadian Association for  
Neuroscience) University of Toronto $500

2009                      
Restracomp Travel Award, $1,000
The Hospital for Sick Children

2009                      
BRAIN Research Symposium, winner (oral presentation) $200
University of Toronto

2008                      
Restracomp Travel Award, $1,000
The Hospital for Sick Children

2008 - 2009                         
Ontario Graduate Scholarship (declined) $15,000

2007 - 2008                         
Restracomp Award, $20,000
The Hospital for Sick Children

2007 - 2008                         
Peterborough K.M. Hunter Graduate Studentship Award (declined) $20,000

2007 - 2008                         
University of Toronto Fellowship, $2,000
University of Toronto

2006 - 2007                         
CIHR Frederick Banting and Charles Best Canada Graduate Scholarships, $17,500
Master's Award, CIHR

2006 - 2007                         
University of Toronto Fellowship, $2,000
University of Toronto

2006                                      
Research Training Competition Tuition Bursary, $2,000
The Hospital for Sick Children

2002                                      
Trent University President’s Honour Roll,
Trent University

1999 - 2001                         
Trent University Dean’s Honour Roll,
Trent University

1999 - 2001                         
Trent University Scholarship, $1,000
Trent University

1999                                      
John Pettigrew Award (for English 100), $200
Trent University

1998                                      
Trent University Entrance Scholarship, $850
Trent University
 

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RESEARCH, TEACHING, AND EMPLOYMENT
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October 2012 – Present
Post-Doctoral Fellowship, Rotman Research Institute, Baycrest
Supervisor: Dr. Cheryl Grady

September 2006 – August 2012 
Graduate Student, Dept. of Physiology, University of Toronto
Program in Neurosciences & Mental Health, The Hospital for Sick Children
Supervisor: Dr. Sheena Josselyn

September 2005 – August 2006 
Research Assistant, Kunin Lunenfeld Applied Research Unit, Baycrest
Supervisor: Dr. Paula Rochon

May 2002 – August 2005           
Research Assistant, Psychology Department, Trent University.
Supervisor: Dr. Gordon Winocur

2002                                        
Teaching Assistant, Trent University
PS379 Aging and Cognition and PS375 Neuropsychology
Supervisor: Dr. Jocelyn Aubrey

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ABSTRACTS & POSTERS
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Frontiers in Physiology Symposium (University of Toronto, Department of Physiology) April 13, 2012 (poster)

Society for Neuroscience Annual Conference (Washington, DC, USA) November 14, 2011 (poster)

Molecular and Cellular Cognition Society Meeting (Washington, DC, USA) November 11, 2011 (poster)

The Hospital for Sick Children Research Institute Research Retreat (Toronto, ON, Canada) November 1, 2011 (poster)

Canadian Association for Neuroscience (CAN) Annual Conference (Quebec City, QC, Canada) May 16, 2011 (poster)

Frontiers in Physiology Symposium (University of Toronto, Department of Physiology) April 8, 2011 (poster)

Brain Research and Integrated Neurophysiology Platform Research Day (University of Toronto, Department of Physiology) December 16, 2010 (poster)

Society for Neuroscience Annual Conference (San Diego, CA, USA) November 16, 2010 (poster)

Molecular and Cellular Cognition Society Meeting (San Diego, CA, USA) November 11, 2010 (poster)

Canadian Association for Neuroscience (CAN) Annual Conference (Ottawa, ON, Canada) May 16, 2010 (poster)

Frontiers in Physiology Symposium (University of Toronto, Department of Physiology) April 15, 2010 (poster)

University of Toronto Neuroscience Program (University of Toronto) April 14, 2010 (poster)

Brain Research and Integrated Neurophysiology Platform Research Day (University of Toronto, Department of Physiology) December 16, 2009 (Winner of oral presentations)

Society for Neuroscience Annual Conference (Chicago, IL, USA) October, 2009 (poster)

Molecular and Cellular Cognition Society Meeting (Chicago, IL, USA) October, 2009 (poster)

Frontiers in Physiology Symposium (University of Toronto, Department of Physiology) April 22, 2009 (poster)

Brain Research and Integrated Neurophysiology Platform Research Day (University of Toronto, Department of Physiology) December 10, 2008 (poster)

Society for Neuroscience Annual Conference (Washington, DC, USA) November 16, 2008 (poster)

Molecular and Cellular Cognition Society Meeting (Washington, DC, USA) November 13, 2008 (poster)

Program in Neuroscience Research Day (University of Toronto) April 30, 2008 (poster)

Frontiers in Physiology Symposium (University of Toronto, Department of Physiology) April 24, 2008 (poster)

Brain Research and Integrated Neurophysiology Platform Research Day (University of Toronto, Department of Physiology) December 17, 2007 (poster)

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COMMITTEES AND OUTREACH
Animal Care Committee, The Hospital for Sick Children Research Institute (2009-2010)

Supervise 4th year undergraduate students in University of Toronto’s Human Biology Program, course HMB499Y:
2010-2011: Jane Wu (currently a 1st year graduate student, University of Toronto)
2009-2010: Daniel Corrazolla (currently a 2nd  year medical school student, Queens University)
2008-2009: Colin Kwok (currently a 3rd year medical school student, China)

Science Rendezvous volunteer 2009, 2011, 2012

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